Crossing the Blood-Brain Barrier with 5-HTP

Crossing the Blood-Brain Barrier with 5-HTP

Feb 22, 2011

Serotonin is one of the many neurotransmitters shown to play a key role in various functions including regulating the Circadian rhythm, hormonal function, digestion, metabolism, and mental and emotional health. Recent research has discovered that approximately 90% of the human body’s serotonin is located in the gut, and the remainder is found in the central nervous system. This research shows the correlation between healthy digestion and serotonin production. Serotonin is an inhibitory neurotransmitter, meaning it does not stimulate the brain, but adequate amounts of serotonin are necessary for a stable mood and to balance any excessive excitatory neurotransmitters firing in the brain. In fact, serotonin is a master neurotransmitter that has relationships with, and affects, all major neurotransmitters such as dopamine, norepinephrine, epinephrine, and GABA. It is also the precursor to melatonin, the neurotransmitter responsible for regulating sleep and ovulation patterns. Low levels of serotonin can produce symptoms such as cravings, depression, insomnia, inflammation, irritability, addictive behaviors, menstruation dysfunction, anxiety, hot flashes, and decreased immune function.

Since serotonin cannot cross the blood-brain barrier, brain cells must synthesize their own serotonin from 5-HTP. Seratran is uniquely formulated with the neurotransmitter precursor 5-HTP, which is necessary for optimal serotonin production. It also includes vitamin and mineral cofactors including vitamin C, specific B vitamins, and calcium, which all play a part in the synthesis of serotonin. In today’s society, hectic lifestyles, poor diet, lack of sleep, stress, and genetic predisposition are cofactors that contribute to serotonin imbalances among adults and children. Seratran is a dietary supplement that is designed to provide the body with the resources it needs to maintain a healthy serotonin balance.

For more information, please contact Energetix 800.990.7085 or

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